Topamax Information

Topamax (topiramate)

Topamax is a seizure medication, also called an anticonvulsant. Topamax is used alone or in combination with other medications to prevent seizures in adults and children who are at least 2 years old. Topamax is also used to prevent migraine headaches. Topiramate will only prevent migraine headaches or reduce the number of attacks. It will not treat a headache that has already begun. Topamax may also be used for other purposes not listed in this medication guide.

Is Topamax for me ?

Use Topamax as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Topamax by mouth with or without food.
• Drink plenty of fluids while taking Topamax to prevent kidney stones from forming.
• Swallow Topamax whole. Do not crush, break, or chew before swallowing.
• Do not suddenly stop taking Topamax . Suddenly stopping Topamax may cause seizures to occur more often. If you need to stop Topamax , your doctor will gradually lower your dose.
• If you miss a dose of Topamax, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Are there any side effects of Topamax ?

Get emergency medical help if you have any of these signs of an allergic reaction to Topamax: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

How does Topamax work ?

Seizures may be classified as either partial if they involve only a small portion of the brain or generalized if they involve more of the brain. Topamax is used in combination with other anti-seizure drugs among adults and children aged 2-16 years with partial seizures or generalized tonic-clonic seizures (in which there is prolonged contraction of the muscles of the body that causes rigidity as well as jerking motions). Topamax sprinkle capsules are approved for treatment without other drugs in patients 10 years of age and older. Topamax also is used in patients two years of age and older with seizures associated with the Lennox-Gastaut Syndrome, a severe form of epilepsy which accounts for up to 10 percent of all cases of childhood epilepsy. Children with Lennox-Gastaut Syndrome experience delays in their development and up to dozens of different, mixed types of seizures a day. The most common types of seizures in this syndrome are tonic (stiffening of the body, with the eyes rolling upwards, dilation of the pupils and shallow, irregular breathing), atonic (brief loss of muscle tone and consciousness, causing abrupt falls), myoclonic (sudden muscle jerks), and absence (staring spells).

Topamax Dosage

Most commonly, topamax is started in low doses, 25 or 50 mg per day, and then increased slowly, under a doctor's orders, by 25 to 50 mg per week until an effective daily dose is reached. This slow approach to treatment reduces side effects. In children, the starting dose is up to 25 mg (1 to 3 mg/kg/day), taken nightly for the first week. The dose is then increased at 1 or 2 week intervals by 1 to 3 mg/kg/day. Although the usual adult dose is 200 mg twice daily, some adult patients may begin to see a clinical response at 200 mg per day. Some patients need doses higher than 200 mg daily. In children, the usual dose is 2.5 to 4.5 mg/kg twice daily. Patients should maintain an adequate fluid intake in order to minimize the risk of kidney stones.

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